The 46-year-old man was walking on a footbridge when he fell.
According to the firefighters, he was in cardiac arrest as a result of the accident. Workers at the construction site tried to resuscitate him before =emergency services took over.
However, his died later in the hospital.
An investigation could be initiated by the Occupational Health and Safety Administration in Michigan.
The Little Caesars Arena, which will open in the fall, will be the new home of the Red Wings and Detroit Pistons.